@andrecool-68 said: Can anyone tell me what the problem might be? I gave you a practical step, which would have provided useful information to try to find the problem, had you grabbed that information before deleting/re-unzipping. That information is obviously gone now, so the best anyone can do is guess. And the best guess is still what Don and I were both indicating: a mismatch in apparent paths (two different strings that possibly refer to the same physical drive location: maybe junctions or symbolic links or similar) or a mismatch in real paths (two different portable copies, where the one actively running is not the same as the one your registry was invoking). Modern security prevents the non-elevated registry command from passing data across the “boundary” to the elevated Admin Notepad++ that was running (though if they are using the same path to the executable, as in my experiements where it worked, then the data can cross that boundary) And a “miracle” happened: Not a miracle. your deletion and re-unzip likely got rid of the mismatch that we were trying to help you find. About a month ago there was a situation where the “manage plugins” menu item disappeared. “Plugins Admin”. It would have disappeared because of Mark of the Web. As, IIRC, we told you, about a month ago.