@MeSun310918
Your issue doesn’t belong to this thread.
In this case, Windows already told you all you need to know - most likely your company set that restriction via a domain policy for this specific folder in question, so you must go to the Windows Settings > Privacy & security > Windows Security > Virus & threat protection > Ransomware protection > Manage ransomware protection, and set the notepad++.exe app to be allowed there.
after updating - worked before without any problems with older versions.
Maybe your previous N++ version was older than v8.8.7, where the N++ digital signature changed (new certificate).
What works:
I can use standard Notepad to save files to that location.
Yes. All the Microsoft own binaries (digitally signed by MS) are allowed by default.