Hmm. I wonder if the server doesn’t think your account has permission to access the root directory contents. Maybe try setting the default directory to your account’s “home directory”, and see if that works. Also, try seeing if the same thing happen with a separate *FTP client (maybe FileZilla or WinSCP or something similar)? if it happens with another client, then you will need to talk with the sysadmin or support for the server/provider. If it doesn’t, then the problem is probably too deep for me – you might want to file an issue with the NppFTP plugin’s issue tracker