I’ve found that you can update it, stand alone, or through their platform updater:
http://portableapps.com/support/portable_app#upgrading
[Just install an updated version of NP++ portable, over the current version]
Upgrading a Portable App
Standalone - To upgrade a portable app manually without the PortableApps.com Platform, just browse to the location of the AppNamePortable_x.x.paf.exe file you downloaded.
Double-click the file to start the installation. Follow the on-screen prompts and select the location you’d like to install to.
For upgrades, you should select the parent directory of the AppNamePortable directory in which the app is currently installed.
For example, if the app is within
X:\PortableApps\AppNamePortable,
you’d want to select the
X:\PortableApps directory in the Browse Folder window.
After clicking OK, it should show X:\PortableApps\AppNamePortable. All of your current settings and data will be preserved.
Uninstalling a Portable App
Unlike traditional apps, a portable app isn’t ‘installed’ with an entry in Add/Remove programs, so uninstallation is quick and easy.
Standalone - Delete the AppNamePortable folder to completely remove the app and all its settings.
[A plugin such as Aspell, though, is installed with an entry in Add/Remove programs - there is no way to make it portable with NP++, native or PortableApps]
In the NPP++ native version, made stand alone, you can do this in the menu across the top:
? / Update Notepad++
? / Set Updater Proxy…
The native version of NP++ also has fewer files, and a smaller file size.
I’ll go with that