@Mouaffaq-Al-Baghdadi:
A way to do it would be to copy all of your original data into a new tab, and then act on that tab with the following (as the suggestion will be a destructive replacement).
Step 1: Add a line at the top of the is new tab, containing 2222 only and then press Enter to add a line-ending to this line
Step 2: Add a line at the bottom of the is new tab, containing 1111 only and then press Enter to add a line-ending to this line
Step 3: Perform this Replacement action:
Invoke the Replace dialog (default key: ctrl+h)
Find what zone: ^2222\R(?s).*?^1111\R
Replace with zone: make sure this is EMPTY
Wrap around checkbox: ticked
Search mode selection: Regular expression
Action: Press Replace All button