The v2.00 options were greatly simplified:
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It added options to the Auto Save when list:
☐ File tab changes: If this option is checkmarked on ☑, it saves every time you activate a different tab in Notepad++.
☐ Notepad++ exits: If this option is checkmarked on ☑, it saves when you exit Notepad++.
It removed options for the “autorecover” style of backup – so now it will always overwrite the existing file, rather than creating a recovery file alongside the original. And v2.00 removed the handling of the Unnamed/new Files, forcing you to rely on Notepad++'s native handling of unnamed files (and thus strengthening the argument behind the admonishment to always manually save your unnamed files to a known location as soon as you can, since AutoSave isn’t helping you with that anymore).
Also, if you upgraded from v1.61 or earlier to v2.00, you will need to check your settings, to make sure it’s still set up in a way that functions with your workflow.